Assembly and function of the lambdoid bacteriophage tail: observations from phi 80-lambda host-range phenotypic mixing.
نویسنده
چکیده
The host-range proteins of lambda and phi80, while differing sharply in host-receptor specificity and in sensitivity to phage-killing antiserum, can be assembled into functional phage tail structures of mixed composition.
منابع مشابه
A phi 80 function inhibitory for growth of lambdoid phage in him mutants of Escherichia coli deficient in integration host factor. I. Genetic analysis of the Rha phenotype.
Bacteriophage phi 80 and lambda-phi 80 hybrid phage of the type lambda (QSR)80, in which the rightmost 10% of the lambda genome is replaced by corresponding phi 80 material, are unable to grow lytically in himA and hip/himD mutants of Escherichia coli K12 at 32 degrees. The genetic element responsible for the growth defect, rha, has been mapped to the (QSR)80 region and was located more precise...
متن کاملA phi 80 function inhibitory for growth of lambdoid phage in him mutants of Escherichia coli deficient in integration host factor. II. Physiological analysis of the abortive infection.
Derivatives of phage lambda with the rightmost 3% of the genome (the QSR region) from the related phage phi 80 fail to grow at low temperatures (e.g., 32 degrees) in Escherichia coli hosts deficient in either protein component of IHF (integration host factor), the products of the himA and hip/himD genes. The abortive infection of lambda (QSR)80 in mutants defective for IHF was studied in detail...
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ورودعنوان ژورنال:
- Journal of virology
دوره 12 1 شماره
صفحات -
تاریخ انتشار 1973